On 14 September 2015, it was announced that Whyte would fight old rival Anthony Joshua for the vacant British heavyweight title on 12 December at the O2 Arena in London on Sky Sports Box Office. Joshua was able to use his power to hurt Whyte in the first round. He appeared hurt again in the second round but was able to catch Joshua with a counterpunch and follow it up, leaving Joshua visibly shaken, Whyte also landed several body shots towards the end of the round that winded Joshua further leaving him much less mobile. This continued somewhat in the third round with Joshua still looking tired and stiff legged. As the rounds went on, Joshua regained his composure and took control. Whyte took many hard shots before coming back with his own, his chin has since been lauded by critics. Whyte was rocked again in the seventh round from a heavy right hand to the temple. Joshua was able to follow through and landed an uppercut that put Whyte down through the ropes and knocked him out.